The University of Missouri at Columbia
Chemistry 2050 - Introduction to Organic Chemistry - Fall Semester 2004

Professor Dr. Rainer Glaser
Office 321 Chemistry Building
Telephone (573) 882-0331
Course Web Site
Lab. Lecture
MTW 11:00 - 11:50, 103 Schlundt Hall
F 11:00 - 11:50, 103 Schlundt Hall
First Lecture Friday, August 27, 2004
Office Hours MW 10:00-10:50

Course Goals

Organic chemistry is pervasive in every aspect of modern life. Chemistry is the central science and every science major needs to master chemistry. Many consumer choices, economic choices and political choices require the understanding and competent application of chemical concepts. Chemistry knowledge thus informs both the professional life of a science major as well as his/her life as good citizen in a democratic society. It is the goal of this course to teach students the abilities to ...

[1] Learn the (symbolic) language of organic chemistry.
[2] Develop clear conceptual ideas and quantitative knowledge about the sources, properties, reactions and uses of organic chemical materials.
[3] Access online journals and databases and extract information form these sources.
[4] Understand the historical context and the culture of the field of organic chemistry and to judge your own work and the work by others in that context.
[5] Read the contemporary press and media and learn to identify and place in context any issues which require an understanding of organic chemistry for their complete appreciation.
[6] Enable autodidactic behavior - the utopian goal.

Aristotle's World

Aristotle (384-322 BC) was very wrong ... we are getting better but beware!

The Modern World

Organic Chemistry
A Brief Introduction By Example

A very simple piece of DNA is shown. Understanding DNA is of interest to many areas including Chemistry, Biochemistry, Biology, Medicine, ... and of course Philosophy. To begin to understand anything about this very special molecule we need to analyze the molecule and then test hypotheses we have come up with.

recognize building blocks and functional groups
recognize properties of fragments
connections between building blocks
polymerization of monomer
3d-stereochemistry of monomers & polymers
structure determination

About Learning in Customary Educational Settings

Similarly, no one has been able to confirm any certain limits to the speed with which man can learn. Schools and universities have usually been organized as if to suggest that all students learn at about the same rather plodding and regular speed. But, whenever the actual rates at which different people learn have been tested, nothing has been found to justify such an organization. Not only do individuals learn at vastly different speeds and in different ways, but man seems capable of astonishing feats of rapid learning when the attendant circumstances are favourable. It seems that, in customary educational settings, one habitually uses only a tiny fraction of one's learning capacities. [Emphasis ours]

Excerpt from the Encyclopaedia Britannica

Complexities of Human Learning

Human learning is complex rather than simple. Learners are apt to learn more than one thing at a time. Sometimes this process is conscious, as when one simultaneously or rapidly assimilates many specific items of a whole. More often, the process is entirely or partly unconscious, as when the student learns some "content" consciously but at the same time absorbs unwittingly a great deal more from interrelationships, tones of voice, and so on.

Educators are therefore becoming increasingly concerned with these concomitant learnings. They are aware that the long-term significance of the arithmetical skill that the student consciously learns may be nugatory compared with the importance of what he learns about himself as a learner, about his capacities and limits, about his relationship with his teacher, about power and authority, about his relationships with his fellow students, about equality, collaboration, competition, and friendship. As educators become more knowledgeable about the importance of learning climates, they are impelled to abandon simplified techniques of teaching in favour of a more complex approach that views learning in the context of a matrix of relationships and forces that act upon the student, the teacher, the school, and the community.

Excerpt from the Encyclopaedia Britannica

Course Materials

Course Materials I. Books and Model Sets.

(1) Required: R. C. Atkins and F. A. Carey, Organic Chemistry: A Brief Course, 3rd eddition, 2002, McGraw-Hill, Dubuque, IA. ISBN 0-07-231944-5.

(2) Recommended: Student Solutions Manual to accompany item (1). ISBN 0-07-231945-3.

(3) Required: HGS Molecular Model Set, C Set for Organic Chemistry, W. H. Freeman and Company. ISBN 0716748223.

Course Materials II. Laboratory Teaching Materials.

Educational materials from various sources will be used in the laboratory. Some of the materials were developed by faculty of the Department of Chemistry while other materials are adopted from other sources. For your convenience, all of these materials are available in electronic format at the same location. Hardcopies will be provided to you in the Friday lectures.

Course Materials III. Resources of the World Wide Web & The New York Times.

We will make extensive use of the world wide web as instructional tool. Chemistry is in the News activities, studies of Visualization Centers, explorations of Web Destinations, inspections of Reaction Animations all are web based.

As part of the "Chemistry Is in the News" project, you are required to read The New York Times this semester. The New York Times features a superb science section in its Tuesday edition and, in fact, there are many articles in The New York Times every day that are in some way related to science in general and chemistry in particular. We want to learn to see these connections! In previous semesters, I have frequently based test questions on NYT articles and I will continue this practice. So, keeping up with the Times will be good for your chemistry grade. There are several ways for you to read The New York Times:

[a] Get your daily copy of The New York Times for free through the MU Readership Program (since September 2003). One of the distribution boxes is located in the Memorial Union (close to the ATM) and it requires a valid student ID for access.

[b] Read the online version of The New York Times and print out what you like.


I. Commitment

Chemistry 205 is a demanding course and a commitment has to be made. Merriam Webster's Dictionary defines (noun, 1621) as "a: an agreement or pledge to do something in the future; especially: an engagement to assume a financial obligation at a future date b: something pledged c: the state or an instance of being obligated or emotionally impelled (a commitment to a cause)."

Four hours of lecture and a three-hour lab. For every hour of lecture, you are expected to spend two hours studying and you need at least another two hours to prepare and write-up the laboratory sessions. This means that you are expected to spend 8 hours every week studying for this course in addition to the 7 contact hours. So, this course requires 15 hours of your time every week and this needs to be clear to you from the start. And before tests you might want to put in a few extra hours on top of that. While this course is demanding, it also is fair in that there will be clear expectations as to what you need to do.

Just coming to lecture and putting in a few hours before a test is a strategy that does not work in chemistry. There have to be a permanent effort and a planned commitment of time to spend on studying chemistry.

II. Lectures

Try to read the material before it is covered in class. We want to "talk about chemistry" in class. After the lecture, read the material again and test yourself, possibly in small groups. If uncertainties remain, review the material again, talk to one of the teaching assitants, or come to see me during office hours.

III. Laboratory

The 3-hour laboratory sessions constitute an essential part of Chemistry 2050 and six sections are offered. Experiments will be discussed in the Friday lecture of the week preceeding the performance of the experiment. For details about the laboratory component of Chemistry 2050, see In The Laboratory.

A    8:00-10:50   Thursday   A308 (3-0-eight)  Papiya
B    2:00- 4:50   Tuesday    A307              John
C   11:00- 1:50   Thursday   A307              John  
D    2:00- 4:50   Thursday   A307              Delshanee 
E    8:00-10:50   Tuesday    A307              Papiya
F    8:00-10:50   Thursday   A307              Delshanee

IV. Collaborative Group Activities

Chemistry is very much like a language. You need to learn the structures and the names of compounds and their properties. This is much like learning the spelling and the meaning of a new word in a foreign language. Then you need to learn the rules governing the reactions of these molecules. There is a grammar to chemistry just like there is grammar in language. Nobody would expect a language student to be able to speak the language after "attending lectures" and "studying the book." A language is learned by "speaking in the language" and the same is true for chemistry. You need to put yourself in situations in which you "talk chemistry." It is the purpose of the Chemistry 205 Collaborative Groups to engage the students in collaborative learning activities and to train and develop their ability to work with their peers. Talking chemistry with your peers, working together, obtaining feedback obtained from your peers, all of these mechanisms will provide opportunities for more active learning, will create the framework for support and constructive criticism, and will teach you valuable lessons on group dynamics.

Student groups of 4-6 students are best and it is best if the members of a group are in the same laboratory section. Labs will be done in pairs and groups will be either 2 or 3 pairs of lab buddies. Look to the members of your group to discuss problems you encounter in the lectures or in the laboratory, compare notes, discuss strategy in problem-solving ... and exercise your chemistry knowledge through these active learning activities.

The groups are self-selected and there are some obvious ways to form groups. Some of you might know each other from courses previously taken together, from living in the same dorm, engaging in the same sports, you might know each other from Greek Life, and so forth. Others might be new to Columbia and MU and might not know anybody in this course as yet. In either case, to find other students to create your groups just approach other students and ask whether they might be interested in joining you. Practical aspects (where does (s)he live, what times is (s)he available, ...) are as important as personal matters (do you think you can get along with this student ...) and your estimate of his/her ability and motivation (is this student likely to contribute to the group ...).

V. Computer-Laboratory

You will have the opportunity to engage in a variety of computer-assisted learning activities. These activities will include working with web-based teaching materials and hands-on molecular drawing and modeling. Instructions and introductions to these activities will occur in the Friday lecture periods. You can pursue the web-based activities later on at any time from any place. The molecular drawing and modeling exercises require special software only available in the computer laboratory of the Department of Chemistry.

We recommend that you study the Visualization Centers in small groups. It is one of the aims of the web-based teaching materials to improve your understanding of structure and to begin to see how structure affects function. The Visualization Centers provide accurate structures of selected molecules in an online format. Each structure can be viewed from user-selected perspective and a mini-tutorial is provided for guidance. Talk about the minitutorials and talk about the structures displayed.

The establishment of relevance is an important co-factor in the learning process. An excellent way to establish the relevance of the content of Chemistry 2050 is by way of connecting the course content to the real world. We will study Chemistry is in the News items to construct these connections between chemistry and society. These teaching materials are based on the philosophy that "newspapers mirror society and newspaper allow to construct the important relations between society and chemistry." There is one "news item" per chapter and it includes one published newspaper article, editorial comments, and questions. The editorial comment section often includes links to high quality sites on the world wide web.

Further guidance to WWW sites is provided by the Portal to Organic Chemistry on the World Wide Web. Ths collection of chemistry related links is permanently under construction. You are invited to tell me about sites you would like to have added.

Molecular drawing and modeling activities will make use of ChemOffice. ChemDraw is a structure drawing program and Chem3D is a versatile molecular modelling program. You will learn how to draw structures and include those in reports. You will learn how to find the "best" structure of a molecule and you can visualize the molecular orbitals and many other properties.

The materials covered in these web-based teaching materials and/or computer-assisted activities will be revisited in the tests. About 25 percent of each test will be concerned with these materials.

V. Group Workshops & CIITN Computer Training Sessions (this section added 10/20/04)

The Group Workshop Sections are held by one of the Peer Learning assistants (PLA) once a week. There are no Group Workshops in the weeks for which CIITN Computer Training Sessions are scheduled. It is expected that one representative from each group will attend one of these sections, this representative can be the same or a different students each week. Three sections are held in a local coffee shop on campus, a session lasts approximately half an hour, two are offered in the evening and one during the 9-to-5 day time. Only seven students may sign up for any one section each week. This small number allows the group workshop sections to be more personal with benefits for the students and the PLA. Five main topics that are addressed each week and they are: 1) how are your groups working, 2) how are your current projects going amd/ot how are the assessments going, 3) are there any concerns with the lectures/class, 4) are there any concerns with specific lecture/book material, and 5) are there any concerns with the labs. At the end of each Group Workshop Section the students complete a survey to record attendance and to obtain feedback to improve future Group Workshop Sections.

The CIITN Computer Training Sessions are held by one of the Peer Learning assistants (PLA) at the times of the assignments of the three CIITN modules. The sessions take about 45-60 minutes and they will in the Chemistry department's computer laboratory. Every student needs to attend these sessions and five alternmative sections are offered with a maximum of 25 students per session. It is recommended that all studnets of a group attend the same session (as much as is possible). In these sessions the assignments is explained and resources are taught and explored that are needed to accomplish the assignment. At the end of the session the students complete a mini-survey to record attendance and to provide feedback to inform the planning of future CIITN Computer Training Sessions.

VI. Exercises

Work as many problems in the book as you like. You are not required to return the answers. You should work these problems on your own, discuss difficult issues and check answers with the members of your collaborative group.

VII. Meet Your Teacher

If there is interest from the students, every other week or so, there will be a Chem 2050 lunch. These lunches will happen at the Memorial Union, at Hudson Hall, and other places. And, perhaps, even at the University Club! Everybody is welcome!

Examinations and Grading

The Greek philosopher Socrates argued that the unexamined life is not worth living.

      Examinations / Activities      Points
      Exam 1 (in-class & take-home)    100
      Exam 2 (in-class & take-home)    100
      Exam 3 (in-class & take-home)    100 
      Exam 4 (in class)                 50 

      Collaborative Activities          20 (10 * 2) for Workshop Participation
      Assignment I. Abstract            50 by Ms. Carson
      Assignment II. Models             50 by Ms. Koetting   
      Assignment III. CIITN Project    100 by Peer Review

      In the Laboratory                240 (12 * 20) by TA  
      Lab Performance                   10 by TA 
      Lab Test                         150 by Lab Coordinator                     

      Final                            200 

      Course Total                    1170 YOUR GRADE WILL BE BASED ON THIS NUMBER 

      Extra Point Opportunities   
      Consent Form                       0 
      Demographics Questionnaire        10 (req. submitted consent form)
      Habit Sheet                       10 (req. submitted consent form) 
      Assessment Questionnaire          10 (req. submitted consent form) 

      Course Total                    1200        

Grading is based on an absolute grading scheme to reward competency rather than competition.
        Grade A+ above 95%, grade A above 90%, grade A- above 85%, 
        Grade B+ above 80%, grade B above 75%, grade B- above 70%,
        Grade C+ above 65%, grade C above 60%, grade C- above 55%,
        Grade D+ above 50%, grade D above 45%, grade D- above 40%;  
        Grade F  less than 40%.  

In concert with the policy of the Department of Chemistry, there will be no make-up exams. If you know in advance, that you will not be able to take an exam for a certain reason, talk to the instructor before the date of that test. If you miss a test without a legitimate reason, you will receive a score of zero points for that test.

Relevant University Regulations

Final Examination. The final examination is scheduled for Tuesday, December 16, 2003, 1-3pm. Time and date of the final examination are determined by Article V of the Academic Regulations which are designed to protect students from irregularities in the administration of final examinations. The following two excerpts from Article V are relevant to this graduate class. (1) No teacher will hold an examination during any time other than the regular meeting time of the class or the time as approved by the Registrar for both final and multi-section examinations. The only exception is that examinations in courses numbered 400 and above may be conducted at any time agreeable to both the teacher and the students. (2) No examination may be held during Stop Day.

Academic Honesty. Academic honesty is fundamental to activities and principles of a university. All members of the academic community must be confident that each person's work has been responsibly and honorably acquired, developed, and presented. Any effort to gain an advantage not given to all students is dishonest whether or not the effort is successful. The academic community regards academic dishonesty as an extremely serious matter, with serious consequences that range from probation to expulsion. When in doubt about plagiarism, paraphrasing, quoting, or collaboration, consult the course instructor. Proven academic dishonesty will be reported to the Provost for Academic Affairs and the student's Dean. (8/2/00)

Instructional Communication Policy. MU is determined to promote effective communication between students and academic personnel involved in instruction. To report communication problems with the instructor or the teaching assistants, please contact Dr. John Adams, Director of Undergraduate Studies, Department of Chemistry; e-mail:

Compliance with the Americans with Disabilities Act. If you need accommodations because of a disability, if you have emergency medical information to share with me, or if you need special arrangements in case the building must be evacuated, please inform me immediately. Please see me privately after class, or at my office. To request academic accommodations (for example, a note taker), students must also register with Disability Services, AO38 Brady Commons, 882-4696. It is the campus office responsible for reviewing documentation provided by students requesting academic accommodations, and for accommodations planning in cooperation with students and instructors, as needed and consistent with course requirements. For other MU resources for students with disabilities, click on "Disability Resources" on the MU Home Page (upper right) or visit the Disability Services web site. (1/20/03)

Excellence is a Habit