Tylenol Cold
Chewable Tablets

Antihistamine, Nasal Decongestant, Fever Reducer, Pain Reliever,

Runny Nose, Stuffy Nose, Sore Throat, Sneezing, Fever


Tylenol Cold for Children contains active ingredients as well as inactive ingredients.

The active ingredients include
                               Chlorpheniramine Maleate
                              &n bsp; Pseudoephedrine HCl
The inactive ingredients include
                              &n bsp; Aspartame
                              &n bsp; Basic Polymethacrylate
                              &n bsp; Cellulose
                              &n bsp; Cellulose Acetate
                              &n bsp; Citric Acid
                              &n bsp; D&C Red #7
                              &n bsp; FD&C Blue #1
                              Hydroxypropyl Methylcellulose
                              &n bsp; Magnesium Stearate
                              &n bsp; Mannitol

Active Ingredients


Acetaminophen is a commonly used therapeutic drug with analgesic and antipyretic properties.  It is a metabolite of phenacetin. It is used to treat mild to moderate pain and fever, including simple headaches, muscle aches, and mild forms of arthritis. It is useful for patients who cannot take aspirin, such as those taking anticoagulants or suffering from gastrointestinal ulcers or bleeding disorders.  Acetaminophen appears to interfere with the action of prostaglandins, substances in the body that cause inflammation and make nerves more sensitive to pain impulses. It also relieves fever, probably by acting on the heat-regulating center of the brain.

                              &n bsp;         Chemical Equation
                                ;         Molecular Weight
                                ;         Function
Pain Reliever and Fever Reducer
                                ;         Physical Properties
   White crystal powder

169 degree melting point

Very slightly soluble

                              &nb sp;     Chemical Structure


       Chlorpheniramine Maleate

Chlorpheniramine Maleate is used to relieve symptoms of allergies.  It works by  blocking the effects of histimine, a naturally occuring substance that causes swelling, itching, sneezing, watery eyes, hives and other symptoms of allergic reactions. Chloropheniramine Maleate is an alkylamine type.
                               &nb sp;        Chemical Equation
                                ;         Molecular Weight
                                ;         Function
Antihistamine-relieves symptoms of allegies
                                ;         Physical Properties
White crystaline solid

130-135 degree melting point
                              &n bsp;       Chemical Structure


         Pseudoephedrine HCl

Pseudoephedrine HCl  relieves nasal or sinus congestion caused by colds, sinus infection, hay fever, or other respiratory allergies. It narrows and constricts blood vessels to reduce the blood flow to swollen nasal passages and other tissues, which reduces nasal secretions, shrinks swollen nasal mucous membranes, and improves airflow in nasal passages.

                                  Chemical Equation
                                ;  Molecular Weight
                                ;  Function
Nasal Decongestant
                                ;  Physical Properties
180-182 degree melting point
                           Chemical Structure


Inactive Ingredients

Aspartame is largely made of two building blocks of protein called amino acids. The two amino acids are aspartic acid and phenylalanine (as the methyl ester). Aspartic acid helps our bodies convert food to energy, and infants and children especially need the phenylalanine found in such foods as milk and meats for building muscles. The third ingredient, called a methyl ester, is also found naturally in fruits, tomato juice and other foods.
                               &nb sp;        Chemical Equation
                                ;         Molecular Weight
                                ;         Function
Low Calorie Artificial Sweetner
                              &n bsp;      Physical Properties
248-250 degree melting point
                              &n bsp;     Chemical Structure


     Basic Polymethacrylate
       (Methacrylic Acid)

Methacrylic acid is widely used in clear polyacrylate plastics and in surface coatings such as acrylic latex paints.  It is also used in making methacrylate resins.
                                     Chemical Equation
                                              Molecular Weight
                     &nbs p;                 Physical Properties
Colorless crystals or clear liquid

16 degree melting point

163 degree boiling point
                                      ;         Chemical Structure


Citric Acid

Traces of citric acid can be found in numerous plants and animals because it is a nearly universal intermediate product of metabolism and large amounts of the acid can be found in juices of citrus fruits.  From here it is then precipitated by the addition of lime; the resulting calcium citrate is treated with sulfuric acid to regenerate the citric acid. It is added to some foods and beverages to produce a pleasant acid flavor; it is also used in medicines, in making blueprint paper, in textile printing, and as a polishing agent for metals.

                             &nb sp;      Chemical Equation
                                   Molecular Weight
serves as a laboratory reagent
                                   Physical Properties
White crystals
Moisture sensitive
                                      Chemical Structure


D&C Red #6

The color additive D&C Red No. 6 is principallythe disodium salt of 3-hydroxy-4-[(4-methyl-2-sulfophenyl)azo]-2-naphthalenecarboxylic acid (CAS Reg. No. 5858-81-1). To manufacture the additive, amino-5-methylbenzenesulfonic acid is diazotized with hydrochloric acid and sodium nitrite. The diazo compound is coupled in alkaline medium with 3-hydroxy-2-naphthalenecarboxylic acid. The resulting dye precipitates as the disodium salt.

                               ;     Chemical Equation
                                ;              Molecular Weight
                                ;              Function
Red Dye for Cherry Flavored Tylenol
                                ;               Chemical Structure


FD&C Blue #1

FD&C Blue #1 is a synthetic color additive and is considered "certified."   FD&C Blue No. 1, or Brilliant Blue FCF, is a triphenylmethanecolor. This dye is water soluble and is poorly absorbed by the body, making it readily usable in most foods. Many studies have been conducted on FD&C Blue No. 1, and it has shown no evidence of carcinogenicity and no adverse effects other than 15 percent less body weight. Also, no adverse reproductive or developmental effects have been exhibited. The FDA has concluded the FD&C Blue No. 1 to be safe.

                              &n bsp;           Chemical Equation
                                                  Molecular Weight
Blue Dye for Grape Flavored Tylenol
Used in food, drugs and cosmetics
                                                  Physical Properties
283 degree melting point
                                            Chemical Structure


Magnesium Stearate

                              &nb sp;    Chemical Equation
                                               Molecular Weight
Used as a food additive
                                       Physical Properties
white powder
130-150 degree melting point
density is 250-320 g/l



Mannitol is a nutritive sweetener (compared to non-nutritive sweeteners such as aspartame and saccharin which provide no nutrients or calories), stabilizer, humectant and bulking agent in foods and supplements. It can be derived from the Manna plant or from seaweed.Mannitol is an osmotic agent and has a high diuretic potential.  It is one of several carbohydrates classified as a sugar alcohol or polyols. Because of mannitolís osmotic properties, it promotes the movement of fluid from the intracellular into the extracellular space. In emergency care, mannitol is used in the treatment of head injury to decrease cerebral edema and intracranial pressure, and in the promotion of urinary excretion of toxic substances.

                                     &nb sp;        Chemical Equation
                                ;              Molecular Weight
                                ;              Function
nutritive sweetner
osmotic diuretic
                                ;      Chemical Structure


For more information on any of the previous organic molecules just click on the name of the product above in blue.

This website was created by Lindsey Murray for Dr. Rainer Glaser, Organic Chemistry Professor at the University of Missouri.  The data displayed for each of these organic molecules (unless otherwise cited by the blue links) can be found on

No data found for the following inactive ingredients:
                        Cellulose Acetate
                        Hydroxypropyl Methylcellulose

July 12, 2001