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DOXYLAMINE SUCCINATE

C21H28N2O5

388.46

Color : white powder

Solubility: >=10 g/100 mL at 22 C

Melting Pt. : 103-108 C

Boiling Pt. : N/A

FUNCTION : ANTI-ALLERGIC AGENT; ANTIHISTAMINE; SEDATIVE

TOXICITY(LD50) :

METHOD OF ADMINISTRATION

ANIMAL TESTED

DOSAGE

ORAL

MOUSE

470 mg/kg

INTRAVENOUS

MOUSE

62 mg/kg

Side effects can include: gastro intestinal disturbances such as nausea, vomiting, diarrhea or constipation, anorexia or increased appetite, and epigastric pain.  Aditional toxicity data available here.

SPECIAL NOTES : Commonly used in over-the-counter sleeping pills, such as Unisom.