Chemistry 212 --- Things-To-Study
Chapter 18: Enols and Enones
You are expected to be familiar with the material described in chapter
18, the associated problem assignments, and the associated GTQ
worksheets. Material described in that chapter but omitted in lecture
will not be pertinent to the test.
Specific Important Topics
Enols and Their Reactions
Enolization (typical pKa values of A&Ks, mechanisms)
Halogenation of A&Ks (in basic and acidic media)
Alkylation of A&Ks (including in particular the use of enamines)
Aldol Condensation and related reaction (central topic!)
Chemistry of alpha,beta-Unsaturated Aldehydes and Ketones.
The conceptual differences between 1,2- and 1,4-addition with particular
(a) 1,2- and 1,4-additions of organometallic compounds
(b) Michael Reaction
(c) Robinson Annulation
Note that there will be synthesis as well as disconnection problems.