The Fischer Esterification Module

Theme Molecule Name Chemical Formula
Alcohol methanol (S) H3C-OH
Carboxylic Acid formic acid (S) H-COOH
Activated Carboxylic Acid protonated formic acid 1 (S) [H-C(OH)2]+
Activated Carboxylic Acid protonated formic acid 2 (S) [H-C(OH)2]+
Alcohol Adduct of Activated Acid MeOH adduct of prot. formic acid 1 (S) [H-C(OH)2(HOMe)]+
Alcohol Adduct of Activated Acid MeOH adduct of prot. formic acid 2 (S) [H-C(OH)2(HOMe)]+
Tetrahedral Intermediate Intermediate (S) H-C(OH)2(OMe)
Water Adduct of Activated Ester Water adduct of prot. ester (S) [H-C(OH)(OMe)(OH2)]+
Protonated Ester Protonated methyl formate (S) [H-C(OH)(OMe)]+
Ester s-trans Methyl formate (S) HCOOMe, C-O s-trans
Ester s-cis Methyl formate (S) HCOOMe, C-O s-cis
Water water (S) HOH
Hydronium Ion hydronium ion (S) H3O+

Note, conformations 2 of the protonated formic acid and of its MeOH adduct are used in the animation. Both are lower in energy than the alternatives.