Glaser Group News

Boldness has genius, power and magic in it. Johann Wolfgang von Goethe


A. People & Positions | B. Fresh from the Press! | C. Group@Conferences | D. Meetings | E. Assets | F. Folklore


A. People & Positions

Alumni News from Rich Nichols: Rich attended the University of Missouri-Columbia Medical School, a year of internship in Internal Medicine at Washington University in St. Louis followed, and he is now in his second year of a dermatology residency at the University of Virginia.

Congratulations to Ms. Papiya Majumdar & Mr. Sanjay Dutta, new parents of Shayak, a sweet little boy born December 6, 2005. Welcome to the world, Shayak! Papiya, get well soon.

Ms. Rebecca Docherty, exchange student from The University of Manchester, joined the group for AY05-06. She will be working with the materials group and John Sui will be her primary mentor. Welcome to the group!

Congratulations to Dr. Hong Wu and Dr. Nathan Knotts, and special Congratulations to our first-ever M.A. graduate (and new mom) Ms. Kathleen Carson.

Glaser group alumni in academia: Dr. Grace Chen (Ph.D. MU 1996, PD ETH Zuerich 1997, Humboldt PD Heidelberg 1998) was promoted to Associate Professor at Providence University, Shalu, Taiwan. Dr. Michael Lewis (Ph.D. MU 2001, PD Harvard 2001-4) wins Assistant Professorship at St. Louis University! Dr. Mitchell Anthamatten (B.S. MU 1996, Ph.D. MIT 2001, PD LLNL 2001-3) wins Assistant Professorship at the University of Rochester! Dr. Sundeep Rayat (Ph.D. MU 2002, PD OSU 2004-5) wins Assistant Professorship at Kansas State University. Dr. Jonathan Rhoad (Ph.D. OSU 2004, LS-PD MU 2005) wins Assistant Professorship at Missouri Western State University.


B. Fresh From The Press!

1-Methyl-1,3,6-triphenyl-7-(2-phenylpropenyl)-1,2-dihydronaphthalene
Yongqiang Sui, Charles L. Barnes, and Rainer Glaser
Structure Communication, Acta Cryst. C 2006, 62, 98-100. PDF.

Coordinate Covalent Ph-to-B Bonding in Phenylborates and Latent Formation of Phenyl Anions from Phenylboronic Acid
Rainer Glaser and Nathan Knotts
Article, J. Phys. Chem. A 2006, 110, 1295-1304. PDF. (Web Release Date: September 15, 2005.)

Dipole Parallel-Alignment in the Crystal Structure of a Polar Biphenyl: 4'-Acetyl-4-Methoxybiphenyl (AMB)
Rainer Glaser, Nathan Knotts, Zhengyu Wu, and Charles Barnes
Article, Cryst. Growth Des. 2006, 6, 235-240. PDF. (Web Release Date: September 17, 2005.)
Online Visualization: Molecular and Crystal Structures.

Oxanosine is a Substrate of Adenosine Deaminase. Implications for the Quest for a Toxicological Marker for Nitrosation Activity
Papiya Majumdar, Hong Wu, Peter Tipton, and Rainer Glaser
Article, Chem. Res. Toxicol. 2005, 18, 1830-1841. PDF.

Nitrosative Cytosine Deamination. An Exploration of the Chemistry Emanating from Deamination with Pyrimidine Ring-Opening
Sundeep Rayat, Ming Qian, and Rainer Glaser
Article, Chem. Res. Toxicol. 2005, 18, 1211-1218. PDF.

Nitrosation Chemistry of Pyrroline, 2-Imidazoline, and 2-Oxazoline: Theoretical Curtin-Hammett Analysis of Retro-Ene and C-X Cleavage Reactions of alpha-Hydroxy-N-nitrosamines
Hong Wu, Richard N. Loeppky, and Rainer Glaser
Article, J. Org. Chem. 2005, 70, 6790-6801. PDF.

Chemistry Is in the News. Taxonomy of Authentic News Media Based Learning Activities
Rainer E. Glaser and Kathleen M. Carson
Article, Int. J. Sci. Educ. (IJSE) 2005, 27, 1083-1098. PDF

Cytosine Catalysis of Nitrosative Guanine Deamination and Interstrand Cross-Link Formation
Rainer Glaser, Hong Wu, and Michael Lewis
Article, J. Am. Chem. Soc. 2005, 127, 7346-7358. PDF.

Additivity Schemes in Conformational Analysis. Concept and Demonstration
Zhengyu Wu and Rainer Glaser
Article, J. Theo. & Comput. Chem. (JTCC) 2005, 4, 373-381. PDF

Amino-Effect on the Protonation of beta-Aminoacrylonitrile
Hong Wu and Rainer Glaser
Communication, Chem. Res. Toxicol. 2005, 18, 111-114. PDF.

Demonstration of an Alternative Mechanism for G-to-G Cross-Link Formation
Ming Qian and Rainer Glaser
Article, J. Am. Chem. Soc. 2005, 127, 880-887. PDF.


C. 230th ACS National Meeting, Washington, D.C., Aug. 28 - Sept. 1, 2005.

1. 17O-Labeling studies as integral accompaniment to 18O-studies
Rainer Glaser and Papiya Majumdar
Contributed Lecture, Division of Organic Chemistry.


229th ACS National Meeting, San Diego, CA, March 13 - 17, 2005.

1. Chemistry Is in the News: Evolution of a modern curriculum
Rainer E. Glaser, Kathleen M. Carson, Yongqiang Sui, Brian Hodgen, Cecelia Koetting, Susan M. Schelble, Uri Zoller, Gregor Fels, and Shelly Rodgers
Invited Lecture, "NSF Catalyzed Curriculum Development" Symposium, Dr. Susan Hixson, Organizer, Division of Chemical Education.

2. Chemistry Is in the News: Engaging chemistry and policy through the news
Rainer E. Glaser and Kathleen M. Carson
Contributed Lecture, Division of Chemical Education.

3.Lateral synthones in crystal engineering: 1,4-Diphenylbutadienes and their azine analogs
Rainer Glaser and Yongqiang Sui
Contributed Lecture, Division of Organic Chemistry.

4. Crystal Engineering with arene-arene interactions and halogen bonding to achieve perfect dipole-parallel alignment in molecular crystals
Rainer Glaser and Nathan Knotts
Contributed Lecture, Division of Organic Chemistry.

5. Facilitating and balancing collaborative group work in the large lecture class
Rainer E. Glaser, Cecelia Koetting, Yongqiang Sui, Kathleen M. Carson
Poster Presentation, Division of Chemical Education.


228th ACS National Meeting, Philadelphia, PA, August 22 - 27, 2004.

1. Nitrosative DNA base deamination: What can we learn from gas phase ion chemistry?
Rainer Glaser, Ming Qian, Papiya Majumdar, Hong Wu, and Nathan Leigh

2. Anisotropic effects of the DNA environment on the rotational barrier of 5-cyanoamino-1H-imidazole-4-carboxylic acid
Rainer Glaser and Hong Wu

3. Oxanosine: A substrate of adenosine deaminase
Rainer Glaser, Papiya Majumdar, Hong Wu, and Peter Tipton

4. Acylic cyanoimine or pyrimidine? Synthesis, reactions and toxicological relevance of 5-cyanoamino-4-imidazolecarboxamide
Rainer Glaser and Ming Qian

5.Chemistry is in the News: Facilitating science collaboration and communication
Rainer Glaser, Zhengyu Wu, Yongqiang Sui, Brian Hodgen, and Kathleen Carson

6.Chemistry is in the News workshops: Faculty preparation and development
Rainer Glaser, Kathleen Carson, Brian Hodgen, Zhengyu Wu, Yongqiang Sui, Susan Schelble, and Eric Lupo
Invited Lecture, "NSF Sponsored Center for Workshops in the Chemical Sciences and the Impact of the Workshops on Curriculum Development" Symposium, Dr. David Collard, Organizer.

7.Exploring the competition-collaboration continuum in collaborative group work
Rainer Glaser, Brian Hodgen, and Kathleen Carson
Contributed Lecture, "Learning Centered Approaches Across the Curriculum" Symposium, Dr. Richard S. Moog and James N. Spencer, Organizers.

8.Internationalization at home through Chemistry is in the News
Rainer Glaser, Kathleen Carson, and Brian Hodgen
Contributed Lecture, "Learning Centered Approaches Across the Curriculum" Symposium, Dr. Richard S. Moog and James N. Spencer, Organizers.


18th Biennial Conference Chemical Education, Ames, Iowa, July 18 - 22, 2004.

1.Chemistry is in the News Workshop at the 18th BCCE, Iowa State University, Ames, Iowa, July 18 - 22, 2004. Workshop Organizers: Rainer Glaser, Department of Chemistry, University of Missouri-Columbia, and Susan Schelble, Department of Chemistry, University of Colorado-Denver.

2. Chemistry is in the News: Teaching Students to Read Science
Brian Hodgen, Kathleen Carson, Zhengyu Wu, Yongqiang Sui, Rainer Glaser
Invited Lecture, "Scientific Literacy for the New Century" Symposium, Dr. Gabriela Weaver, Organizer, 18th Biennial Conference on Chemistry Education, BCCE, Iowa State University, Ames, Iowa, July 20, 2004.

3. Science is in the News: High School Chemistry Enrichment Opportunity
Kathleen Carson, Brian Hodgen, Zhengyu Wu, Yongqiang Sui, Rainer Glaser
Invited Lecture, "K16 Collaborations" Symposium, Dr. Penny Gilmer, Organizer, 18th Biennial Conference on Chemistry Education, BCCE, Iowa State University, Ames, Iowa, July 19, 2004.


CERM2004, Indianapolis, June 2004.

1.Synthesis of Adenine in Interstellar Space: A Mass Spectroscopy and Theoretical Study
Rainer Glaser, Brian Hodgen, Hong Wu, Elliot McKee, Dean Farrelly, Papiya Majumdar, and Ming Qian.
Invited Lecture, Chemistry in Interstellar Space Symposium, Lewis Snyder and Clifford Dykstra, Organizers. 36th ACS Central Regional Meeting, IUPUI Hotel and Conference Center, Indianapolis, Indiana, June 2, 2004.

2. Imidazole ring formation in gas phase ion chemistry
Brian Hodgen, Hong Wu, and Rainer Glaser
Contributed Poster, Division of Physical Chemistry. 36th ACS Central Regional Meeting, IUPUI Hotel and Conference Center, Indianapolis, Indiana, June 2, 2004.

3. 18O-Labeling study of nitrosative guanosine deamination: Identification of the oxanosine precursors
Sundeep Rayat, Papiya Majumdar, Peter Tipton and Rainer Glaser
Contributed Lecture, Division of Biological Chemistry. 36th ACS Central Regional Meeting, IUPUI Hotel and Conference Center, Indianapolis, Indiana, June 3, 2004.

4. Structure-isomeric G-to-G cross-links
Ming Qian and Rainer Glaser
Contributed Lecture, Division of Biological Chemistry. 36th ACS Central Regional Meeting, IUPUI Hotel and Conference Center, Indianapolis, Indiana, June 4, 2004.


NSF-DUE CCLI Program Conference, April 2004.

"Chemistry is in the News: Preparation for Science Communication"
Rainer E. Glaser, Kathleen Carson, Brian Hodgen, Zhengyu Martin Wu, Yongqiang John Sui, Susan Schelble, and Eric Lupo
NSF-DUE CCLI Program Conference Hyatt Regency Crystal City, Arlington, Virginia, April 16-18, 2004.


55th Regional ACS Meeting, SERMACS 2003, November 16 - 19, 2003.

1. Rational Design of Polar Molecular Organic Materials
Rainer Glaser, Nathan Knotts, and John Sui
Invited lecture in the "Organic Materials Chemistry" Symposium, P. Kaszynski, Organizer, Division of Organic Chemistry.

2. Chemistry is in the News. Preparation for Science Communication
Rainer Glaser, Zhengyu Wu, Kathleen Carson, Brian Hodgen, and John Sui
Symposium on NSF Sponsored Programs, Division of Chemistry Education


38th Midwest Regional ACS Meeting, Columbia, Missouri, November 5 - 7, 2003.

Contextual Testing in Chemistry: Preparation for the MCAT
Rainer E. Glaser, Brian Hodgen, and Kathleen Carson
Invited lecture in the "Organic Chemistry Education" Symposium, B. Brent, Organizer, Division of Chemical Education


226th National ACS Meeting, New York City, September 7-11, 2003.

1. Experimental demonstration of a new mechanism for dG-to-dG crosslink formation
Rainer Glaser and Ming Qian

2. Pyrimidine ring-opening in nitrosative guanosine deamination: Experimental evidence from 18O-labeling studies
Rainer Glaser, Sundeep Rayat, and Papiya Majumdar

3. College Science Education as Preparation for Science Communication
Rainer E. Glaser, Zhengyu Wu, and Susan Schelble
Contributed lecture in the "Communicating Chemistry" Symposium, C. Kotz & Leonard Fine, Organizers

4. Postmodern Science Communication - Challenge and Mandate
Rainer E. Glaser
Invited lecture in the "Instructional Developments in Organic Chemistry Education" Symposium, M. Mosher, Organizer


38th National Organic Symposium, IU, Bloomington, IN, June 8 - 12, 2003.

1. Synthesis of 5-Cyanoimino-Imidazole-4-Carboxamide And Their Cyclization To Purines.
Ming Qian and Rainer Glaser

2. Pyrimidine ring-opening in nitrosative guanosine deamination: Experimental evidence from 18O-labeling studies
Sundeep Rayat and Rainer Glaser


224th National ACS Meeting, Boston, August 18-22, 2002.

1. 5-Cyanoimino-4-imidazolecarboxamide and nitrosative guanine deamination: Experimental evidence for pyrimidine ring-opening during deamination.
Rainer Glaser and Ming Qian

2. Deamination of cytosine revisited: Experimental evidence for uracil formation by way of ring-opening and recyclization.
Rainer Glaser and Sundeep Rayat

3. Nitrosative guanine deamination: An ab initio study of the carbodiimide - cyanoamine tautomerization in the pyrimidine ring-opened intermediate.
Rainer Glaser and Sundeep Rayat

4. Endogenous nitrosation chemistry in carcinogenesis: An ab initio theoretical study of decomposition reactions of cyclic a-hydroxynitrosamines.
Rainer Glaser, Hong Wu, and Richard Loeppky



6th World Congress of Theoretically Oriented Chemists, Lugano, Switzerland, Palazzo dei Congressi, August 4-9, 2002.

1. Nitrosative DNA base deamination: A theoretical study of the hydrolysis of the DNA base diazonium ions. Activated Reactions Without Transition States.
Rainer Glaser, Sundeep Rayat, Zhengyu Wu, Brian Hodgen, and Karen Williams

2. The "Chemistry is in the News" Project: Teaching Chemistry in the Context of Real-World Issues"
Rainer E. Glaser [a], Zhengyu Wu [a], Deborah L. Hume [b], and James Groccia [c]
[a] Department of Chemistry, [b] Department of Psychology, and [c] Program for Excellence in Teaching, University of Missouri-Columbia, Columbia, Missouri, 65211



223rd National ACS Meeting, Orlando, Florida, April 7-11, 2002.

1. "Chemistry is in the News: Communicating Chemistry via News Media Based Learning Activities"
Rainer E. Glaser, Department of Chemistry, and James Groccia, Program for Excellence in Teaching
Division of Chemical Education. Invited lecture in the Symposium on "Communicating Chemistry," C. Kotz & Leonard Fine, Organizers.

2. "Nitrosative Adenine Deamination: A Theoretical Study of the Decomposition Pathways of Adeninediazonium Ion."
Rainer Glaser, Brian Hodgen, and Sundeep Rayat
Division of Computers in Chemistry.

3. "Theoretical Study of Phenylboronic Acids as a Source of Phenyl Anions."
Rainer Glaser and Nathan Knotts
Division of Computers in Chemistry.

4. "Computational Analysis of the Origin of the Disorder in a Highly Dipole-Parallel Aligned Molecular Crystal."
Rainer Glaser, Zhengyu Wu, and Michael Lewis
Division of Computers in Chemistry.


34th Midwest Theoretical Chemistry Conference, Supercomputing Institute for Digital Simulation and Advanced Computation, Minneapolis, Minnesota, October 4-6, 2001.

1. Theoretical Studies of DNA Base Deamination.
Rainer Glaser, Sundeep Rayat, Michael Lewis, Brian Hodgen, and Karen Williams

2. Bimolecular Nucleophilic Substitution of an Anion by an Anion. A Theoretical Study of Phenylboronic Acids as a Source of Phenyl Anions. (PDF)
Nathan Knotts and Rainer Glaser

3. Nitrosative Adenine Deamination. A Quantum Mechanical Study of the Decomposition Pathways of Adeninediazonium Ion. (PDF)
Brian Hodgen, Sundeep Rayat and Rainer Glaser

4. Endogenous Nitrosation Chemistry in Carcinogenesis. Retro-Ene Reactions of Cyclic alpha-Hydroxynitrosamines. (PDF)
Hong Wu, Rainer Glaser and Richard Loeppky

5. Benzene Quadrupolarity and Arene-Arene Interactions. (PDF)
Zhengyu Wu and Rainer Glaser

6. Nitrosative Guanine Deamination: A Quantum Mechanical Study of Carbodiimide - Cyanoamine Tautomerization in the Pyrimidine Ring-Opened Intermediate. (PDF)
Sundeep Rayat and Rainer Glaser


221st National ACS Meeting, San Diego, April 1-5, 2001.

1. "Theoretical Studies of DNA Deamination. Pyrimidine Ring-Opening and Recyclizations
in the Nitrosative Deaminations of Guanine, Cytosine and Adenine."
Rainer Glaser, Sundeep Rayat, Michael Lewis, Thomas Carl, and Brian Hodgen
Division of Computers in Chemistry. Invited lecture in the Symposium on "Computational Studies of Reaction Mechanisms and Enzyme Modes of Action", Tim Clark, Organizer.

2. "Philosophy, Pedagogy And Taxonomy Of News Media Based Authentic Learning Activities."
Rainer E. Glaser
Division of Chemical Education. Invited lecture in the Symposium on "Organic Chemistry Teaching in the New Century", C. Kingsbury, Organizer.
This lecture was featured in Chemical & Engineering News on April 16, 2001, in the article "Teaching Organic Chemistry" by Pamela S. Zurer.

3. "Benzene Quadrupolarity and Arene-Arene Interactions."
Rainer Glaser and Zhengyu Wu, Division of Computers in Chemistry.

4. "Cytosine to Uracil Mutation Revisited. Theoretical and Experimental Mechanistic Studies of the Nitrosative Cytosine Deamination."
Rainer Glaser and Sundeep Rayat, Division of Organic Chemistry.