POSTDOCTORAL POSITION IN ORGANIC CHEMISTRY/TOXICOLOGY AT THE UNIVERSITY OF MISSOURI-COLUMBIA

An NIH-funded postdoctoral position is available to study the chemical mechanisms of deamination of the DNA bases. Independent syntheses of selected postulated intermediates will be carried out and their chemistry will be explored in aqueous media. The reactions of these postulated intermediates with synthetic oligonucleotides will be studied to explore the possibilities of novel DNA adduct formation and of cross-link formation. Candidates with proven synthetic skills and experience with oligonucleotide chemistry are encouraged to apply. Experience with HPLC and LCMS is advantageous. The opportunity exists for computational research in conjunction with the experimental studies. Excellent communication skills in English are required. Applicants should send curriculum vitae and have three letters of recommendation sent separately to Dr. Rainer Glaser, Associate Professor, Department of Chemistry, University of Missouri-Columbia, Columbia, MO 65211. Applications can be made by email to glaserr@missouri.edu.