DR. Kattesh V. Katti

Kattesh V. Katti

Professor of Radiology & Physics
Senior Research Scientist MU Research Reactor

Email:

KattiK@health.missouri.edu

Phone:

(573) 882-5656

Fax:

(573) 884-5679

Office:

103, Alton Building

Mailing
Address:

Radiopharmaceutical Sciences Institute
Rm. 103, Alton Buildings
301 Business Loop 70 (W)
University of Missouri-Columbia
Columbia, MO 65212

Research Areas:

Nanoscience and Nanotechnology in Nanomedicine
Metals/Organomatallics In the Development of Cancer Diagnostic and Therapeutic Agents
Biomedical Optical Imaging
New Approaches to Cancer Therapy
New Biomaterials for use in Surgical and Non-surgical Wound Healing applications
Fundamental Aspects of Structure of Water and Water-Alcohol Binary Mixtures

International/National Awards and Honors

On March 20 2008, the Missouri House Representatives awarded Dr. Kattesh V. Katti the coveted ‘Outstanding Missourian’ award for his work in cancer research, Nanomedicine and Green Nanotechnology. Dr. Katti has recently discovered how to make gold nanoparticles using gold salts, soybeans and water – research that has garnered worldwide attention and could have applications in several disciplines. Rep. Ed Robb (R-Columbia) and House Speaker Pro Tem Bryan Pratt (R-Blue Springs) recognized Dr. Katti with the award before the House of Representatives. The award is presented as “acknowledgment of the most accomplished citizens of the state of Missouri” for making an “outstanding contribution to the state or nation.” Outstanding Missourian Award
Dr. Katti has been selected to receive the coveted '2007 Outstanding St. Louis Scientist Fellows Award' by the Academy of Science of St. Louis. The Academy's literature called it "a rare feat to be distinguished in all of these fields simultaneously" and praised Katti's discoveries in the development of gold and silver nanoparticles for applications in nanomedicine.
Dr. Kattesh V. Katti’s Nanomedicine research has been cited by the President of India in his Inaugural Speech at the Global Nanoscience Initiatives on March 16 2006 in New Delhi, India: http://presidentofindia.nic.in/scripts/sllatest1.jsp?id=745
Dr. Kattesh V. Katti has been awarded the 2006 year Gauss Professorship from the Academy of Sciences, Gottingen, Germany
http://www.muhealth.org/~news/2005/katti05.shtml
http://www.columbiatribune.com/2005/Nov/20051110News004.asp

Recent Discoveries

Dr. Katti’s discovery on Nanoparticles production was quoted on the front page of NANO BIOTECH NEWS (Vol. 2; No 48; December 8 2004 http://www.nhionline.net/products/nanobiotechnews/nbn12804wek.pdf)“240 times faster than previous methods; University of Missouri-Columbia researchers make gold, silver nanoparticles in 5-10 minutes”
Dr. Katti’s Nanoscience work was cited in Innovations Report of Germany (http://www.innovations-report.com/html/reports/life_sciences/report-36440.html) as “Nanoparticles to Aid Medical Diagnosis, Therapy”
Dr. Katti’s work was cited in NANO TECHNOLOGY NOW: “MU Researchers Produce Nanoparticles to Aid Medical Diagnosis, Therapy in Fraction of Previous Time” (http://www.nanotech-now.com/news.cgi?story_id=06721)
Dr. Katti’s Nanoscience discovery was cited in: Nano Tsunami: http://www.voyle.net/Nano%20Medicine/Medicine%202004-0058.htm
Dr. Katti’s discovery was cited in one of the major vitamin health sites in the U.S. Dr. Katti’s work do develop a new drug for Wilson’s Disease is featured. https://webmail.um.umsystem.edu/exchweb/bin/redir.asp?URL=http://newvitality.com/Articles.aspx
Dr. Katti’s discovery on the development of a new drug for treating Wilson’s disease was cited in: http://www.newswise.com/articles/view/507813/. This discovery was covered in National/International news media.

Educational Background

Ph.D 1984, Indian Institute of Science, Bangalore, India
M.S.Ed. 1979, Regional College of Education, Mysore, India
B.S.(Chemistry)1977, Karnatak University, India

Recent Publications:

Vijaya Kattumuri, Kavita Katti, Sharanya Bhaskaran, Evan J. Boote, Stan W. Casteel, Genevieve M. Fent, David J. Robertson, Meera Chandrasekhar, Raghuraman Kannanand Kattesh V. Katti, Naturally Occuring Gum Arabic as a Phyto Construct for the Stabilization of Gold Nanoparticles: In Vivo Pharmacokinetics and X-ray Contrast Imaging Studies, Small, 2, 333 2007.
V. Kattumuri, M. Chandrasekhar, and S. Guha, K. Raghuraman , K. V. Katti, K. Ghosh and R. J. Patel, Agarose-stabilized gold nanoparticles for surface-enhanced Raman spectroscopic detection of DNA nucleosides, Appl. Phys. Lett, 88, 153114, 2006.
K. Raghuraman, Rahing V, Cutler C, Pandrapragada R, Katti K.K, Vijaya Kattumuri, J. David Robertson, Stan J. Casteel, Silvia Jurisson, Charles Smith, Evan Boote, and Katti, K. V., Nanocompatible Chemistry toward Fabrication of Target-Specific Gold Nanoparticles, J. Am. Chem. Soc., 128, 11342-11343, 2006.
K. V. Katti, K. Raghuraman, Rahing V, Cutler C, Pandrapragada R, Katti K.K, Vijaya Kattumuri, J. David Robertson, Stan J. Casteel, Silvia Jurisson, Evan Boote, Hybrid Nanoparticles In Molecular Imaging and Therapy, Supplement D of the Czechoslovak Journal of Physics–Proceedings of the 15th Radiochemical Conference, 56, Supplement D, 56, D23, 2006.
N. Pillarsetty, K. Raghuraman, C. Barnes, K. V. Katti, Design, Synthesis and Chemistry of Sterically Non-Demanding Primary Bis-Phosphines, J. Am. Chem. Soc, 127, 331-336, 2005.
K. Raghuraman, N. Pillarsetty, K. R. Prabhu, K. K. Katti and K. V. Katti, Unprecedented rhodium-mediated catalytic transfer hydrogenation of a phosphonate functionalized olefin in ecofriendly media, Inorganica Chimica Acta, 357, 2933-2938, 2004.
K. V. Katti, N. Pillarsetty, K. Raghuraman, New Vistas in Chemistry and Applications of Primary Phosphines, Topics in Current Chemistry, 229, 121-141, 2003.
K. Raghuraman, K. K. Katti, L. J. Barbour, N. Pillarsetty, C. L. Barnes, K. V. Katti, Characterization of Supramolecular (H₂O)₁₈Water Morphology and Water-Methanol (H₂O)₁₅(CH₃OH)₃ Clusters in a Novel Phosphorus Functionalized Trimeric Amino Acid Host. J. Am. Chem. Soc., 125(23), 6955-6961, 2003.
N. Pillarsetty, K. K. Katti, Hoffman, T. J., Volkert, W. A., Katti, K. V., Kamei, H., Koide, T. In vitro and in vivo antitumor properties of Tetrakis((trishydroxymethyl)phosphine)gold(I) chloride. J. Med. Chem., 46(7), 1130-1132, 2003
K. K. Kothari, K. Raghuraman, N. Pillarsetty, T. J. Hoffman, N. K.Owen, K. V. Katti, W. A. Volkert, Syntheses, in vitro and in vivo characterization of a^99mTc-(I)-tricarbonyl-benzylamino-dihydroxymethyl phosphine (NP₂) chelate. App. Rad. Iso., 58(5), 543-549, 2003
K. K. Kothari, N. K. Pillarsetty, K. V. Katti, Volkert, W. A. Characterization of complexation reactions of mono- and bidentate-hydroxymethyl phosphine ligands with the organometallic ^99mTc(I)(OH₂)₃ (CO)₃⁺SYNTHON. Radiochim. Acta 91, 53-57, 2003.
K. Raghuraman, N. Pillarsetty, W. A. Volkert, C. Barnes, S.Jurisson and K. V. Katti. Exceptional Kinetic Propensity of Hydroxymethyl Phosphanes toward Rh(III) Stabilization in Water. J. Am. Chem. Soc., 124, 7276-7277, 2002.
K. V. Katti, K. Raghuraman, N. Pillarsetty, S. R. Karra, R. J. Gulotty, M. A. Chartier and C. A. Lanhoff. First examples of Azaphosphanes as Efficient Electron Donors in the Chemical Architecture of Thermally Stable New Nonlinear Optical Materials. Chem. Mat., 14, 2436-2438, 2002.
K. K. Kothari, H. Gali, K. R. Prabhu, N. Pillarsetty, N. K. Owen, K. V. Katti, T. J. Hoffman and W. A. Volkert. Synthesis and Characterization of ^99mTc and ¹⁸⁸Re- complexes with a diamido-dihydroxymethylenephosphine-based bifunctional chelating agent. (N₂P₂-BFCA) Nucl. Med. Biol., 29, 83-89, 2002.
H. Gali, T. J. Hoffman, G. L. Sieckman, N. K. Owen, K. V. Katti, and W. A. Volkert. Synthesis, Characterization, and Labeling with ^99mTc/¹⁸⁸Re of Peptide Conjugates Containing a Dithia-bisphosphine Chelating Agent, Bioconjugate Chem., 12(3), 354-363, 2001.

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